Antithrombin is the most important anticoagulant protein in the body, and hereditary deficiency is associated with a markedly increased risk of acquiring venous thromboembolic disease. Therefore, analysis of antithrombin activity is a central element in thrombophilia testing. Current diagnostic methods identify reduced amounts of antithrombin (quantitative defects) but are less efficient in diagnosing non-effective antithrombin (qualitative defects). This paper lines up the current guidelines and potential sources of error in the analysis of antithrombin.
Det här är ett utplock av en intressant artikel från KBN – Nr. 1 – vol. 37 – 2025.